Yazar "Uludağ, Damla" için listeleme
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Antioxidant activity and anti-cancer effects of bilberry (vaccinium myrtillus l.) fruit extract on gastric cancer, ags cell line
Karakaş, Nihal; Okur, Mehmet Evren; Sağır, Tuğba; Uludağ, Damla; Polat, Derya Çiçek; Karadağ, Ayşe Esra (Ankara University, 2022)Objective: Vaccinium myrtillus L. fruits are consumed as food. This research was aimed to evaluate V. myrtillus methanol extract antioxidant and cytotoxic activities and determine its anti-cancer potential to further study ... -
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines
Onur Sucu, Bilgesu; Koç, Elif Beyza; Şavluğ İpek, Özgecan; Mirat, Afranur; Almas, Furkan; Güzel, Melike Aybala; Doğan, Berna; Uludağ, Damla; Karakaş, Nihal; Durdağı, Serdar; Güzel, Mustafa (Elsevier Inc., 2022)Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of ... -
Hedefe yönelik olarak geliştirilen toksin füzyonunun çeşitli kanser hücrelerinde in vitro tedavi edici etkisinin incelenmesi
Uludağ, Damla (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2021)Kanser hastalığı, tüm toplumlarda yaygın olarak görülmesine rağmen; genomik değişkenlik, tümörün nüks etmesi, kanser hücrelerinin heterojenitesi, sistemik toksisite gibi nedenlerden ötürü uygulanan tedavi yöntemleri yetersiz ... -
IL13 fused pseudomonas exotoxin targets various cancers in vitro
Uludağ, Damla; Karakaş, Nihal (International Institute of Anticancer Research, 2021)Background/Aim: Pseudomonas exotoxin (PE) is one of the most widely used toxins in the construction of therapeutic fusion proteins in pre-clinical studies followed by phase trials. In principle, PE acts by blocking protein ... -
Investigation of antioxidant and cytotoxic activities of Opuntia ficus-indica (L.) Mill. fruit extract
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Uludağ, Damla; Çiçek Polat, Derya (Istanbul University, 2019)Opuntia ficus-indica fruits are claimed to possess several health-beneficial properties. This study was carried out to determine the phytochemicals as well as to compare antioxidant activity and cell viability of the ... -
Mesenchymal stem cell-based COVID-19 therapy: Bioengineering perspectives
Karakaş, Nihal; Üçüncüoğlu, Süleyman; Uludağ, Damla; Karaoğlan, Birnur Sinem; Shah, Khalid; Öztürk, Gürkan (MDPI, 2022)The novel pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Mesenchymal stem cells (MSCs) are currently utilized in clinics for pulmonary inflammatory ... -
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
Uludağ, Damla; Bay, Sadık; Onur Sucu, Bilgesu; Şavluğ İpek, Özgecan; Mohr, Thomas; Güzel, Mustafa; Karakaş, Nihal (Frontiers Media S.A., 2022)Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ...